DO inhibitor
VX-11e Compound CompositionNLG919Find Out More>>
NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in mobile phone-free of charge assays. Phase 1.
Associated Items: Indoximod, INCB024360 analogue
TNF-α inhibitor
Trovirdine (LY-300046) Compound ConstructionCPI-1189Get More Information>>
CPI-1189(REN-1189) is really a TNF-α discharge inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
Connected Goods: CX691 , Substance 4
Antiepileptic Medicine
DB07268 Compound StructureValrocemideLearn More>>
Valrocemide(Tv set-1901), is surely an antiepileptic medication (AED). Valrocemide carries a large spectrum of anticonvulsant activity and promising probable like a new AED.
Associated Merchandise: Lvguidingan , NS 638
VEGFR Inhibitor
BML-210 Chemical StructureSU 5205Learn More>>
SU 5205 can be a VEGFR2 inhibitor.
Relevant Merchandise: PF-CBP1 , SR-3029
PDGFR Inhibitor
AMG-337 Chemical ConstructionNSC 86429Discover More>>
SU-4312, also referred to as DMBI, can be a powerful and picky inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are .8 and 19.4 μM respectively). SU4312 unexpectedly safeguards against MPP(+) -induced neurotoxicity via picky and primary inhibition of neuronal NOS.
Connected Goods: I-CBP112 , GK921
IKr Channel Blocker
JNJ-42165279 Compound CompositionCK-1752Discover More>>
Sematilide, also referred to as CK-1752, is really a class III antiarrhythmic. It really is a picky postponed rectifier K+ recent (IKr) channel blocker. It inhibits rapidly triggering Ik in guinea pig atrial myocytes, contributing to the prolongation of activity possible length and refractoriness.
Related Items: XL-652 , WAY 200070