Cyclopamine Compound ConstructionCyclopamineLearn More>>
Cyclopamine is really a particular Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 tissue.
Study highlight: Contact with cyclopamine stimulates pancreatic growth in embryonic chicks. (Kim SK, et,al. PNAS, 1998, 95: 13036-13041.)
This system comes in : Bioactive Substance Collection, Normal Compound Collection
TWS119 Chemical FrameworkTWS119Find Out More>>
TWS119 is a GSK-3β inhibitor with IC50 of 30 nM in the cell-free assay able to inducing neuronal differentiation and could be of use to come mobile biology.
Analysis spotlight: TWS119, a 4,6-disubstituted pyrrolopyrimidine that could stimulate neurogenesis in murine ESCs. (Ding S, et,al. PNAS, 2003，100(13): 7632-7637. )
The product includes in : Bioactive Compound Library
Nicotinamide Chemical StructureNicotinamideFind Out More>>
Nicotinamide (Vitamin B3), a drinking water-soluble vitamin, is undoubtedly an active aspect of coenzymes NAD and NADP, and in addition work as an activator of sirtuins.
Investigation spotlight: nicotinamide enhanced the generate of differentiation of Embryonic Stem Tissues to pancreatic endocrine cells (Lumelsky N,et,al.Research, 2001, 292(5520): 1389-1394 )
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