Small Molecules, Big Functions

Cyclopamine Compound ConstructionCyclopamineLearn More>>

Cyclopamine is really a particular Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 tissue.

Study highlight: Contact with cyclopamine stimulates pancreatic growth in embryonic chicks. (Kim SK, et,al. PNAS, 1998, 95: 13036-13041.)

This system comes in : Bioactive Substance Collection, Normal Compound Collection

TWS119 Chemical FrameworkTWS119Find Out More>>

TWS119 is a GSK-3β inhibitor with IC50 of 30 nM in the cell-free assay able to inducing neuronal differentiation and could be of use to come mobile biology.

Analysis spotlight: TWS119, a 4,6-disubstituted pyrrolopyrimidine that could stimulate neurogenesis in murine ESCs. (Ding S, et,al. PNAS, 2003,100(13): 7632-7637. )

The product includes in : Bioactive Compound Library

Nicotinamide Chemical StructureNicotinamideFind Out More>>

Nicotinamide (Vitamin B3), a drinking water-soluble vitamin, is undoubtedly an active aspect of coenzymes NAD and NADP, and in addition work as an activator of sirtuins.

Investigation spotlight: nicotinamide enhanced the generate of differentiation of Embryonic Stem Tissues to pancreatic endocrine cells (Lumelsky N,et,al.Research, 2001, 292(5520): 1389-1394 )

This system consists of in : Approved Medicine Local library, Normal Substance Local library

Testing libraries to determine more functionally unique modest substances!

Contains 3071 little molecule materials

A unique collection of 1700 approved prescription drugs

Includes 640 all-natural substances

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