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Homology-based DNA Repair Inhibitor

YU238259

YU238259 is actually a novel inhibitor of homology-reliant DNA fix(HDR), but fails to hinder non-homologous end-joining (NHEJ), in mobile phone-centered GFP reporter assays.

Associated Items:Bucladesine sodium sea salt

Hsp90 Inhibitor

PF-04929113 Mesylate

PF-04929113 Mesylate, a prodrug of SNX-2112, is definitely an orally productive Hsp90 inhibitor, using a Kd of 41 nM, plus induces Her-2 deterioration, by having an IC50 of 37 nM.

Connected Goods: Resminostat hydrochloridel

Histone methyltransferase Inhibitor

A-196

A-196 can be a powerful and picky inhibitor of SUV420H1 and SUV420H2 with IC50 principles of .025 and .144 μM, correspondingly a lot more than 100-retract selective over other histone methyltransferases and non-epigenetic focuses on..

Associated Items: Ac-CoA Synthase Inhibitor1

Ephrin Receptor inhibitor

ALW-II-41-27

ALW-II-41-27 can be a innovative Eph receptor tyrosine kinase inhibitor, used for malignancy treatment.

Related Goods: Pimodivir , MS049

Tyrosine Kinases inhibitor

Sitravatinib

Sitravatinib (MGCD516) is a novel modest molecule inhibitor aimed towards multiple RTKs involved in traveling sarcoma cell expansion, including c-Package, PDGFRβ, PDGFRα, c-Satisfied, and Axl.

Associated Goods: Miriplatin ,RAD140

Product or service Catalog

Compound Collection

45 types of compound libraries for top throughput evaluating and articles verification.

Investigation Regions

Proteases/Proteasome

Chromatin/Epigenetic

JAK/STAT signaling

Tyrosine Kinase/Adaptors

PI3K/Akt/mTOR Signaling

MAPK Signaling

Apotosis

Ubiquitination

Angiogenesis

Immunology/Soreness

DNA Damage/DNA Maintenance

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