PAC-1 CAS No. 315183-21-2
PAC-1 is actually a successful procaspase-3 activator with EC50 of .22 μM and also the original small molecule seen to directly trigger procaspase-3 to caspase-3.
Pifithrin-α CAS No. 63208-82-2
Pifithrin-α is undoubtedly an inhibitor of p53, suppressing p53-dependent transactivation of p53-open genes.
A-1210477 CAS No. 1668553-26-1
A-1210477 is really a strong and discerning MCL-1 and Bcl-2 inhibitor with Ki and IC50 of .454 nM and 26.2 nM, correspondingly,>100-retract selectivity over other Bcl-2 family.
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