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DO inhibitor

VX-11e Compound CompositionNLG919Get More Information>>

NLG919 can be a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in cell-cost-free assays. Period 1.

Related Merchandise: Indoximod, INCB024360 analogue

TNF-α inhibitor

Trovirdine (LY-300046) Compound ConstructionCPI-1189Get More Information>>

CPI-1189(REN-1189) is really a TNF-α discharge inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.

Connected Goods: CX691 , Substance 4

Antiepileptic Medicine

DB07268 Compound StructureValrocemideLearn More>>

Valrocemide(Tv set-1901), is surely an antiepileptic medication (AED). Valrocemide carries a large spectrum of anticonvulsant activity and promising probable like a new AED.

VEGFR Inhibitor

BML-210 Chemical substance CompositionSU 5205Discover More>>

SU 5205 is really a VEGFR2 inhibitor.

Related Goods: PF-CBP1 , SR-3029

PDGFR Inhibitor

AMG-337 Substance StructureNSC 86429Learn More>>

SU-4312, often known as DMBI, can be a powerful and particular inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 principles are .8 and 19.4 μM respectively). SU4312 unexpectedly safeguards against MPP(+) -induced neurotoxicity via selective and straight inhibition of neuronal NOS.

Related Merchandise: I-CBP112 , GK921

IKr Route Blocker

JNJ-42165279 Compound StructureCK-1752Learn More>>

Sematilide, often known as CK-1752, can be a school III antiarrhythmic. It really is a particular slowed rectifier K+ existing (IKr) route blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of activity prospective length and refractoriness.

Associated Items: XL-652 , WAY 200070

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