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Warm Materials in Protease Inhibitor Nearby collection

proteasome

MG-132

CAS No. 133407-82-6

MG-132 is certainly an inhibitor of proteasome with IC50 of 100 nM from the cellular-absolutely free assay, and likewise inhibits calpain with IC50 of 1.2 μM.

Bortezomib

CAS No. 179324-69-7

Bortezomib (PS-341) is actually a solid 20S proteasome inhibitor with Ki of .6 nM in the portable-cost-totally free assay.

Carfilzomib

CAS No. 868540-17-4

Carfilzomib (PR-171) is definitely an permanent proteasome inhibitor with IC50 of 5 nM in ANBL-6 cells, proven preferential in vitro inhibitory durability up against the ChT-L method within the β5 subunit, but virtually no influence on the PGPH and T-L regimens.

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